• 35, Ballygunge Circular Road, Kolkata-700019

Department of Biotechnology and Dr. B. C Guha Centre for Genetic Engineering and Biotechnology

History

Year of Establishment : 1997

History of the department :
b_c_guha.jpgThe Guha Centre for Genetic Engineering and Biotechnology (GCGEB) has been named after the legendary Dr. Biresh Chandra Guha, one of the most celebrated teachers of Calcutta University and the father of modern Biochemistry in India. As a fitting tribute to this great visionary who laid the foundation stone for teaching and research in Biochemistry and Biotechnology in the country, Calcutta University established the Dr. B. C. Guha Centre for Genetic Engineering & Biotechnology with the unflinching support of Dr. (Mrs.) Phulrenu Guha, the illustrious wife of late Prof. Guha as well as an active social worker and an ex- Minister of Social Welfare, Govt. of India, who sold her personal properties including her residential building to donate money (Rs. 35 lakhs) to the University of Calcutta for the development of the Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology. Dr. B. C. Guha Centre for Genetic Engineering & Biotechnology was established in 1991 (resolution of the Syndicate, item No. 3, dated 30.10.90 followed by resolution No. 6, dated 27. 8. 1991). The activity of the Centre was initiated by further donations from students, associates and well wishers of Late Prof. Guha.

The M.Sc Program in Biotechnology of the Calcutta University started in the  humble 1200 square feet room in the University campus in Ballygunge (Taraknath Palit Sikhsha Prangan) on December 31, 1997 with intake of six students.

The Centre as well its M.Sc Program in Biotechnology gradually received worldwide recognition and accolade and with that came an encouraging flow of moral and financial support both from abroad and the Government of West Bengal. This witnessed the establishment of an entirely new wing (4th floor) in the same campus opposite to the existing Geography Department.

The new wing, built to meet the needs of state-of-the-art research in Biotechnology and Genetic Engineering was inaugurated by the Honorable Chief Minister of West Bengal, Shri Buddhadeb Bhattacharya on March 22, 2005 and marked the beginning of an entirely new chapter in the history of Calcutta University and its research and teaching program in applied bioscience. Since the onset, the department caters 10 students per batch who receive a master’s degree in Biotechnology upon completion of the course.

In the year 2008, a new Department of Biotechnology was formed which merged with the GCGEB for its operations and administrative control.

Special award/ recognition from UGC or related statutory body : Among the departments of the University declared ‘University with Potential for Excellence’ by UGC.

Academic

Faculty members :

Name Designation Area of specialisation Email
Dr. Gopal Chakraborty
[Profile]
 Assistant Professor Protein structure-function, Biophysical Chemistry, and Cancer Cell Biology gcbcg@caluniv.ac.in
Dr. Koustubh Panda
[Profile]
  Professor Nitric oxide & NitricOxide Synthase Physiology  and Regulation, Inflammatory Lung Diseases, Disease Proteomics  & Arsenicosis kpbcg@caluniv.ac.in
Dr. Rajat Banerjee
[Profile]
Assistant Professor Protein structure-function relation, Protein-nucleic acid interaction rbbcgc@gmail.com
Dr. Anindita Seal
[Profile]
Assistant Professor Plant Molecular Biology asbcg@caluniv.ac.in

Emeritus professors and adjunct professors :

Name Designation Area of specialisation
Prof. Indu Bhusan Chatterjee Joint Coordinator, Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology Biosynthesis and function of vitamin C; cigarette smoke-induced various diseases including cancer and their prevention.

Visiting faculty members :

Name Institutions attached with
Prof. Kamales Bhaumik Retired Professor, Saha Institute of Nuclear Physics
Prof. Sampa Das Bose Institute
Debjani Dutta St. Xaviers College
Dr.Soumen Kumar Manna Saha Institute of Nuclear Physics
Prof. D.J. Chattopadhyay Amity University, Kolkata
Professor Utpala Chatterjee Retired Professor
Chittaranjan National Cancer Institute, Kolkata
Dr. Susanta Roy Chowdhury CSIR-Indian Institute of Chemical Biology, Kolkata
Dr. Subrata Banerjee Saha Institute of Nuclear Physics, Kolkata

Courses

Programme Level of study Eligibility Intake capacity
Biotechnology M. Sc A candidate who has passed the 3-year B.Sc. Examination with Honours (Major) in all Life Sciences, Chemistry, Physics, B.Agr, B.Tech (Biotechnology) and M.B.B.S. will be eligible for admission to this course after admission test. 11
Biotechnology Ph.D Candidates with M.Sc in any branch of Life Sciences or Physical Sciences qualifying the departmental Research Eligibility Test (RET)  

Research

Research scholars:

Name Research topic Name of the supervisor Date of registration
Arnab Ganguli Investigating the mechanisms of cytotoxicity of environmental toxicants and anticancer agents Dr. Gopal Chakrabarti 21/02/2013
Ananya Marik Isolation and characterization of protein interactors of BjNRAMP4.1 Metal Transporters using a Split Ubiquitin Yeast Two Hybrid Screen Dr. Anindita Seal 20/12/2011
Chinmay Saha Host- Endophyte interaction contributes to Metal tolerance in Typha angustifolia and enhances growth and nutrition in rice Dr. Anindita Seal 04/08/2011
Debabrata Ghsoh-Dastider Production and characterization of Paclitaxel loaded solid-lipid nanoparticle to increase potency and therapeutic efficacy Dr. Gopal Chakrabarti 22/04/2013
Debasish Nag Characterization of Vibrio cholerae cell Division accessory protein FtsA and screening of small molecules for development of potential FtsA inhibitor (s) Dr. Gopal Chakrabarti 12/12/2013
Dipanwita Das Investigation of role of microtubule targeting agents for development of potential cancer therapeutic agent Dr. Gopal Chakrabarti 14/08/2013
Gairik Mukherjee An investigation of the mechanism of arsenic tolerance by an arsenic accumulator terrestrial plant - Brassica juncea"
Joining date
Dr. Anindita Seal 04/03/2014
Haraprasad Naiya Metal dependent regulation of uptake and homeostasis genes from Typha angustifolia Dr. Anindita Seal 06/08/2012  
Keka sarkar Studies on two species of Coagulase Negative  Staphylococci in relation to their association with polymers of different origin Dr. Rajat Banerjee 2014
Madhumanti Das Functional Characterization of a protein interactor of BjNRAMP4.1 Dr. Anindita Seal 21/ 11/2014
Satabdi Datta  Study of the mechanism of development of taxol resistance in lung cancer cells Dr. Gopal Chakrabarti 12/12/2013
Subhendu Chakrabarty Study of Interaction of Tea Polyphenols with Tubulin-Microtubule System for the Development of Potential Microtubule Inhibitors in Cervical Cancer Cells Dr. Gopal Chakrabarti 22/05/2014
Santanu Banerjee Studies On Cigarette Smoke-induced Pathogenesis: Molecular Mechanisms And Screening Of Smokers At High Risk Prof. I.B.Chatterjee 16/1/2014
Shinjini Ganguli p-Benzoquinone As A Causative  Agent For Cigarette Smoke-induced Pathophysiologies: Prevention By Vitamin C. Prof. I.B.Chatterjee 13/12/2013
Shruti Chakraborty Studies of biophysical and biochemical parameters of human mitochondrial aminoacyl tRNA synthetase Dr. Rajat Banerjee 05/08/2016
Souradipta Ganguly Studies on the Molecular and cellular Mechanism of Cigarette Smoke-induced Alveo-Vascular Damage and Its Possible Prevention Dr. Koustubh Panda 10/07/2013

Projects:

Project title Funding agency Principal investigator Duration Budget
Targeted drug development:  screening of  compounds against major cell division protein FtsZ and its associated protein FtsA of V. cholerae for development of novel lead compound  against cholera DBT, Govt of West Bengal Dr. Gopal Chakrabarti Recently approved (3 years) 26 lacs
Proof-of-Principle Studies and Technology Transfer of a Novel in-vivo Probe for Real-Time Longitudinal Monitoring of Inducible Nitric-Oxide Synthase: Key Enzyme Associated with Human Patho-physiology UGC-UKIERI
(Indo-UK International Grant)
Dr. Koustubh Panda 1.5 years  31 lakhs
Kolkata Biotech Park Project West Bengal Biotech Development Corporation Dr. Koustubh Panda ongoing 380 lakhs
Studying the relation between L-theanine content of Darjeeling and Assam tea and their memory stimulatory effects in in vitro and in-vivo using suitable animal model. Tea Board of India, Ministry of Commerce & Industry, Govt. of India Dr. Koustubh Panda 3 years 40.56
Sanctioned/ Funds Awaited)
Functional Characterization and Validation of Protein Interactors of BjNRAMP4.1 Obtained in Split Ubiquitin Yeast Two Hybrid Screen DST, Govt of India Dr. Anindita Seal 3years   25.09 L
Identification and characterization of endophytic microbe colonization in heavy metal accumulator and tolerant macrophyte Typha angustifolia DBT, Govt. of India Dr. Anindita Seal 3 years 61,50,000
Development of Aspartyl-tRNA synthetase from Entamoeba histolytica as a target for antimicrobial drugs against amibiasis. SERB-DST Government of India Dr. Rajat Banerjee 3 years 29.20 L
Protein Folding Kinetics is a selection force on shaping codon usage bias in the high expression genes DBT-NE Twinning Programme, Government of India Dr. Rajat Banerjee (Joint-PI) Dr. Suvendra Kr. Ray 2 years 42.32 lakhs
Characterization of Aspartyl-tRNA synthetase from Entamoeba histolytica by spectroscopic methods. DBT-NE Twinning Programme, Government of India Dr. Rajat Banerjee (Joint-PI)
Dr. Kalyanasis Sahu
3 years 45.55 lakhs

Collaborations:

Title of the programme Principal collaborator of the department Name and address of the collaborating institution Principal collaborator of the collaborating institution Duration of the programme
IPLS DBT Program Collaboration between Department of Biotechnology, Microbiology and Biochemistry     5 years

Thrust areas in teaching and research of the academic department/centre:

  • Thrust Areas in Teaching:  Medical Biotechnology, Proteomics, Genomics, Bioprocess Engineering, Microbial Biotechnology,  Microbial Biotechnology, Recombinant DNA technology
  • Thrust Areas in Research: Protein Structure-Function, Cancer Biology, Inflammation, Lung Diseases, Drug Discovery/Development, Oxidative damage & Antioxidants, Plant heavy metal tolerance

Research support :

Name of the equipment Brief description Funding agency
Confocal Microscope Zeiss UGC
Fluorescence Activated Cell Sorter BD BioSciences, USA UGC
Ultra Centrifuge benchtop Beckmann Coulter, USA DST-PURSE
Ultra Centrifuge floor Beckmann Coulter, USA NTRF
Tissue Culture facility Plant and Animal Biosafety Hoods – Klenzaid
CO2 Incubators- Heraus
Microscope - Olympus
Sukhomoy & Krishna Lahiri Cancer Foundation

Links :

Contact

Campus : Taraknath Palit Prangan (Ballygunge Science College)

Address for communication : Department of Biotechnology and Dr. B. C Guha Centre for Genetic Engineering and Biotechnology, 4th Floor, 35, Ballygunge Circular Road, Kolkata-700019