Notice Board

Few ITC seats available for National Workshop On Proteomics 2015.

Few ITC seats available for National Workshop On Proteomics 2015. Interested candidates are requested to send their applications as per notification in the IPLS website as early as possible.Selection would be made on merit & first come first serve basis. Selection & registration process should be completed by 31/01/2015.

23rd IPLS SEMINAR SERIES

DATE: 14.01.2015
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Dr Gopal Chakraborti
gopal

National workshop On Proteomics 2015

Click Here to Download Application Form
Click Here to Download Workshop Flyer

Biotica 2015

cu_loogo

University of Calcutta

presents

Biotica 2015

An International Symposium on

Current Perspectives in Life Sciences

Special Event: Felicitation of

Prof. D.J. Chattopadhyay

Date: January 4, 2015

Venue: Centre for Research in Nanoscience and Nanotechnology,

University of Calcutta, JD 2, Salt Lake City, Kolkata 700098

Organized by:

Present and Past Research Scholars of the Chattopadhyay Laboratory

Registration:

Last Date for Registration : December 15, 2014 (prior registration is mandatory)

Registration Fee : Rs. 2000 for Faculty members/delegates
  Rs. 500 for Students and Research scholars
Contact: biotica2015@gmail.com

We look forward to your gracious presence during this event

23rd IPLS SEMINAR SERIES

DATE: 12.11.2014
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Boni Halder
Title of the Talk: My experience in Bangalore Microscopy Course-2014 held at NCBS.
BoniHalder

22nd IPLS SEMINAR SERIES

DATE: 23.04.2014
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Dr. Anirban Siddhanta
Title of the Talk: Nuclear translocation of PIP5Kinase requires reversible SUMO-ylation
Dr. Anindita Ukil

IPLS FacILIty uSage wouLd be PayabLe from 1st MAY, 2014 (Rules & Regulations)

CHARGES:

For CLSM with TIRF attachment, ITC & AFM (only Tapping Mode,Contact Mode & MFM)

  • Internal IPLS: Rs. 100/Slot
  • Non-IPLS CU: Rs. 100/ Slot
  • Outsider: Rs. 750/ Slot
  • For EFM/C-AFM (special modes of AFM using silver paste): Rs. 2000/ sample additional cost.

MALDI – MS & MALDI-MS/MS would be payable from 1st JULY, 2014

  • Internal IPLS: Rs. 100/Sample for MALDI-MS
    Rs. 200/Sample for MALDI-MS/MS
  • Non-IPLS CU: Rs. 100/Sample for MALDI-MS
    Rs. 200/Sample for MALDI-MS/MS
  • Outsiders: Rs. 1000/Sample for MALDI-MS
    Rs. 2000/Sample for MALDI-MS/MS

PAYMENT PROCEDURE:

  • There is no provisional booking; booking is confirmed only after payment is done.
  • For any Instrument, booking will be opened before 1 month and closed before 48 hrs.
  • Cancellation of booking: before 48 hrs.
  • If booking is cancelled due to any Technical Fault after submission of payment, it will be adjusted in the next available slot/day.
  • Instrument usage fee will be submitted in the form of Draft (in favor of “DBT-IPLS MAINTENANCE FUND”) payable at Kolkata.

BOOKING RULES:

  • Non-IPLS CU & Outsider booking is open only on Friday.
  • For any Instrument, 3 consecutive slots/days not allowed.
  • Cancellation before 48 hrs.
  • Clinical samples not allowed.

21st IPLS SEMINAR SERIES

DATE: 26.02.2014
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Dr. Anindita Ukil
Title of the Talk: Role of lipid mediator in modulation of host defence by the protozoan parasite Leishmania donovani.
Dr. Anindita Ukil

IPLS SEMINAR NOTICE

For all the faculty members, scholars and M.sc students of Department of Biochemistry, Biotechnology and Microbiology.

DATE: 03.01.2014
TIME: 4 PM
VENUE: Prof. A.N.Bhaduri Seminar Hall, Department of Biotechnology.
SPEAKER: Dr. Nitish Mahapatra
Associate Professor
IIT Chennai
Title of the talk: Functional genetic variants of Chromogranin A gene alter risk for metabolic diseases.

IPLS SEMINAR NOTICE

For all the faculty members, scholars and M.sc students of Department of
Biochemistry, Biotechnology and Microbiology.

 

DATE: 24.12.2013
TIME: 4 PM
VENUE: Prof. B.C.Guha Seminar Hall, Room No. 740, Department of Biochemistry.
SPEAKER: Dr. Hirak Kumar Patra
Integrative Regenerative Medicine (IGEN) Post Doctoral Fellow
Biosensors and Bioelectronics Center
IFM-Linköpings universitet
Title of the Talk: Smart Biodevices.

IPLS CONFERENCE 2014

Click Here to Download Pdf

20th IPLS SEMINAR SERIES

DATE: 18.12.2013
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Dr. Atanu Maiti
Title of the Talk: Mechanism of Human TDG in DNA Repair and DNA Demethylation.

19th IPLS SEMINAR SERIES

DATE: 26.11.2013
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Dr. Alok Kr. Sil
Dr. Maitrayee Dasgupta

IPLS SEMINAR NOTICE-02.12.13

IPLS SEMINAR SERIES

DATE: 02.12.2013
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Dr. Samyabrata Bhaduri, University of Massachusetts Medical School.
Title of the Talk: Substrate choices of a kinase complex determined by docking motifs.

3rd October, 2013 SEMINAR NOTICE

SEMINAR NOTICE

For all the faculty members, scholars and M.sc students of Department of Biochemistry, Biotechnology and Microbiology.
Date: 3rd October, 2013
Time: 4 PM Onwards
Venue: JJ.Ghosh Memorial Hall (Room No-745, Department Of Biochemistry)

SPEAKER 1

Dr. Swasti Raychaudhuri, Ph.D.
Department of Cellular Biochemistry,
Max Planck Institute of Biochemistry, Germany

Regulation of protein homoeostasis in aging and age-related diseases

Aging can be explained as a chronic stress which is manifested by the progressive decline in protein homeostasis or proteostasis. In age-related diseases proteostasis is further compromised. As the average human life expectancy has increased, so too has the impact of aging and age-related diseases on our society. Thus research on proteostasis maintenance and repair is becoming increasingly important.

However, measuring proteostasis capacity in an elegant way was not possible so far because of unavailability of effective tools which can be used in variety of model systems. To measure and compare the status of the protein quality control system under different conditions, we generated a series of proteostasis sensors. These proteins are increasingly destabilized versions of firefly luciferase, a protein known to depend on molecular chaperones for de novo folding and refolding. GFP-tagged versions of these mutants resulted in aggregates in mammalian cells over-expressing huntingtin exon1 with extended polyQ. These sensors also aggregated with aging in C. elegans confirming gradual collapse of proteostasis. In summary, we have generated a set of widely applicable proteostasis sensors from a single reporter protein. These can be used to obtain snap-shots of dysregulation of proteostasis at different physiological states as well for screening of small molecule modulators of proteostasis for therapeutic intervention.

Exposure to proteotoxic environmental conditions leads to activation of the cytosolic stress response to restore protein homeostasis. This stress response system is mal-functional during aging. Thus inducing cytosolic stress response is a promising strategy to counteract age-related proteostasis collapse. The key feature of this response is the heat shock transcription factor 1 (HSF1) dependent transient expression of stress proteins including molecular chaperones. We have performed a genome-scale RNA interference screen in HeLa cells to identify HSF1 modulators. Our study reveals that signals from multiple key pathways are integrated to regulate the activation and attenuation of HSF1. These include chromatin remodeling, transcription, splicing, membrane signaling, protein folding and degradation. Interestingly, we found that in the absence of a chromatin modifier, namely EP300, HSF1 gets destabilized and inactive. In addition, SILAC based quantitative proteomics experiments revealed that chaperones and proteasome are enriched in nucleus during thermal stress. By quantitative proteomics we also discovered that specific proteasomal subunits interact with transcriptionally active HSF1 during heat stress. Further cell biology experiments highlighted the importance of the proteasomal system in rapid degradation of active HSF1. We found acetylation of specific residues of HSF1 by EP300 is important to protect HSF1 from degradation.

 

SPEAKER 2

Dr. Abhishek Banerjee, D.Phil.
Simons Fellow on Autism and Brain Development
Department of Brain and Cognitive Sciences
Massachusetts Institute of Technology, Cambridge, United States.

Plasticity and Disorders of Neuronal Circuits

Development of the nervous system proceeds through a set of complex checkpoints set by gene-environment interactions. In this talk, I will first highlight mechanisms of timing-dependent plasticity in cortical synapses and how these plasticity rules are spatially-segregated yet temporally-restricted in a compartment-specific manner. I will focus on presynaptic NMDA receptors and their role in presynaptic form of self-depression. Results will demonstrate a novel, anti-Hebbian, non-associative form of presynaptic self-depression at L4-L2/3 synapses in barrel cortex that may precede synapse elimination during early cortical development.

Balance of excitation and inhibition (E/I) plays an important role in neural circuit development and plasticity. In the second half of my talk, I will focus on specific neuronal subtypes and discuss how their properties are disrupted in neuropsychiatric disorders. I will focus on Parvalbumin and Somatostatin-expressing interneurons that play an important role in shaping circuit plasticity and directly affects sensory integration and E/I balance – features that are disturbed in Rett syndrome, an Autism Spectrum Disorder. These two sections will summarize basic physiological properties and plasticity of synapses, how they are altered and how can be used as a biomarker in neuropsychiatric disorders for designing novel therapeutics.

 

"2nd year students are especially encouraged to attend.
Opportunities for Ph.D. may be available."

18th IPLS SEMINAR SERIES

DATE: 11.09.2013
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Prof. Indu Bhusan Chatterjee
Title of the talk: Serendipity and seminal discoveries in medical sciences with particular reference to vitamin C 
Dr. Maitrayee Dasgupta

17th IPLS SEMINAR SERIES

DATE: 20.08.2013
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Dr. Maitrayee Dasgupta
Title of the talk: Two short stories on protein kinase.
Dr. Maitrayee Dasgupta

16th IPLS SEMINAR SERIES

DATE: 10.07.2013
TIME: 4 PM
VENUE: IPLS Office and Training Lab, DBT-IPLS CORE FACILITY.
SPEAKER: Prof. Dhrubajyoti Chattopadhyay
Title of the talk: From Virus O Phobia to Virus O Passion.
  Dhrubajyoti_Chattopadhyay

LIST of SELCETED CANDIDATES for NWIIPLS 2013

Module:AFM

  1. Sushobhan Biswas
  2. Trinath Chowdhury
  3. Deepthi Sudarshan
  4. Upal Das Ghosh
  5. Rupak Kumar Das
  6. Kakali Ghoshal
  7. Chinmay saha
  8. Keka Sarkar
  9. Debabrata Ghoshdastidar
  10. Latika Nagpal

Module:Confocal Microscopy

  1. Kanishendranath Sarkar
  2. Tanmoy Halder
  3. Dipayan Bose
  4. Soumasree De
  5. Haraprasad Naiya
  6. Monolina Sarkar
  7. Anmol Banerjee
  8. Dipanwita Mukherjee
  9. Prativa Naskar
  10. Madhurima Paul

WAITING LIST

  1. Sushobhana Bandyopadhyay
  2. Biswajit Mukherjee
  3. Ujjal Das
  4. Madhubanti Chaudhuri
  5. Somenath Banerjee

All selected candidates are requested to send a draft of Rs.2000/- only, in favour of “DBT-IPLS Maintenance Fund”, payable at Kolkata, by 10th March 2013. Waitlisted candidates will be contacted if any of the confirmed participants withdraw their application.

National Workshop on Imaging, 20th-22nd March

NWI_poster


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IPLS faculty SEMINAR SERIES Presentation by Dr.AnirbanSiddhanta

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